Top 10 causes of cancer!

According to research that our team in Healthowealth has done about the top 10 causes of cancer, cancer is a disease that develops in the human body when certain cells grow uncontrollably and spread to other regions of the body.

Cancer can start in any of the billions of cells that make up the human body. Human cells regularly divide and proliferate to produce new cells as the body requires. Cells die when they get too old or damaged to function and are replaced by new ones.

This well-ordered mechanism can occasionally malfunction, resulting in aberrant or damaged cells developing and replicating when they should not. These cells can develop into tumors, which are masses of tissue. Tumors can be benign or malignant (benign).

Cancerous tumors can assault neighboring healthy tissues and spread to other regions of the body, resulting in the creation of new tumors (a process called metastasis). Cancerous tumors are also known as malignant tumors. Many malignancies create solid tumors, whereas leukemia and other blood cancers do not.

Benign tumors do not spread or infiltrate into adjacent tissues. Benign tumors seldom recur after removal, although malignant tumors do on occasion. Benign tumors, on the other hand, might develop to be exceedingly large. Some, such as benign brain tumors, can cause severe symptoms and even death. Let’s look more accurately at the top 10 causes of cancer.

Cancer Risk Factors

Cancer Risk Factors
Cancer Risk Factors

It is difficult to determine why one person gets cancer while another does not. Certain risk factors, on the other hand, have been shown in scientific studies to increase a person’s odds of developing cancer. Other variables have been linked to a lower incidence of cancer. These are sometimes known as protective risk factors or simply protective factors.

Chemical or other drug exposure, as well as certain behaviors, are all risk factors for cancer. They also include non-controllable elements such as age and family history. A family history of some cancers might point to the possibility of hereditary cancer syndrome.

The vast majority of cancer risk factors are uncovered through epidemiological investigations. In these studies, scientists study large groups of people and compare those who get cancer to those who do not. These studies may demonstrate that people who get cancer are more or less likely than others to act in particular ways or be exposed to certain chemicals. Below are the Top 10 causes of cancer with details.

Top 10 causes of cancer

The list below includes the most well-studied known or suspected top 10 causes of cancer. While some of these risk factors may be ignored, such as growing older, others cannot. Limiting your exposure to avoidable risk factors may aid in the prevention of certain cancers.


Top 10 causes of cancer: Obesity
Top 10 causes of cancer: Obesity

The first case in the list of top 10 causes of cancer, is obesity. Obesity increases the risk of developing malignancies of the breast (in menopausal women), colon, rectum, endometrium (uterine lining), esophagus, kidney, pancreas, and gallbladder. A balanced diet, physical activity, and weight maintenance, on the other hand, may help reduce the risk of some malignancies. Other problems, such as heart disease, type II diabetes, and high blood pressure, can be avoided by implementing these healthy practices.

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Although any cancer treatment can be used as the first line of defense, surgery is the most common initial cancer treatment for the most common malignancies.


Top 10 causes of cancer: Tobacco
Top 10 causes of cancer: Tobacco

Tobacco use is a leading cause of cancer and cancer-related death. Tobacco products and passive smoking include several chemicals that damage DNA, therefore those who use tobacco or are routinely exposed to ambient tobacco smoke (also known as secondhand smoke) have an increased risk of cancer.

Tobacco use causes lung cancer, tracheal cancer, mouth cancer, esophageal cancer, throat cancer, bladder cancer, kidney cancer, liver cancer, stomach cancer, pancreatic cancer, colon and rectum cancer, as well as acute myeloid leukemia.

There is no such thing as a “safe cigarette consumption level.” People who use any type of tobacco product are aggressively encouraged to stop. People who quit smoking, regardless of age, live significantly longer lives than those who continue to smoke. Smoking cessation at the time of cancer diagnosis reduces the chance of death.

Alcohol Consumption

Top 10 causes of cancer: Alcohol Consumption
Top 10 causes of cancer: Alcohol Consumption

Consuming excess alcohol raises your risk of getting malignancies of the mouth, throat, esophagus, larynx (voice box), liver, and breast cancer. The more you drink, the greater the risk. Those who use alcohol and smoke cigarettes have a significantly higher chance of developing cancer.

Drinking should be done in moderation, according to physicians. Moderate alcohol intake is defined by the federal government’s Dietary Guidelines for Americans as one drink per day for women and two drinks per day for men.

Certain red wine components, such as resveratrol, have been suggested to have anti-cancer properties. However, there is no evidence that drinking red wine reduces the risk of cancer.

Inflammation that persists

Top 10 causes of cancer: Inflammation that persists
Top 10 causes of cancer: Inflammation that persists

Inflammation is a natural physiological response that aids in the repair of injured tissue. The inflammatory process begins when injured tissue produces substances. In order to assist heal the damage, white blood cells produce substances that stimulate cells to proliferate and multiply. When the wound heals, the inflammatory process will be completed.

In chronic inflammation, the inflammatory process can begin even when there is no damage and does not end when it should. The cause of the inflammation is not always evident. Chronic inflammation can be caused by persistent infections, unfavorable immune responses to normal tissues, and variables such as obesity. The inflammatory reaction can cause DNA damage, which can lead to cancer. People who have chronic inflammatory bowel diseases such as ulcerative colitis or Crohn’s disease are more prone to acquire colon cancer.

Factor of Age

Top 10 causes of cancer: Factor of Age
Top 10 causes of cancer: Factor of Age

Another case in the top 10 causes of cancer is age. Growing older is a key risk factor for cancer in general, as well as for many particular cancer types. Overall, cancer incidence rates climb steadily with age, from fewer than 25 cases per 100,000 people in the under-20 age group to roughly 350 cases per 100,000 people in the 45–49 age group and more than 1,000 cases per 100,000 people in the 60+ age group.

The average age of a cancer diagnosis, according to the most recent statistical study data, is 66 years. This indicates that half of all cancer cases occur in those under the age of 50, with the other half occurring in people above the age of 50. Frequent cancers follow a similar path.

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Breast cancer, for example, has a median age of 62 years at diagnosis, whereas colorectal cancer is 67 years, lung cancer is 71 years, and prostate cancer is 66 years.


Top 10 causes of cancer: Radiation
Top 10 causes of cancer: Radiation

Ionizing radiation is a form of radiation with enough energy to induce DNA damage and cancer. Ionizing radiation includes radon, x-rays, gamma rays, and other high-energy radiation. Cancer has not been linked to lower-energy, non-ionizing types of radiation, such as visible light and mobile phone energy.

High-energy radiation such as X-rays, gamma rays, alpha particles, beta particles, and neutrons can damage DNA and cause cancer.

These forms of radiation can be emitted during nuclear power plant accidents as well as the creation, testing, and use of nuclear weapons.

Medical techniques that may harm cells and lead to cancer include chest x-rays, computed tomography (CT) scans, positron emission tomography (PET) scans, and radiation therapy. The risks of acquiring cancer as a result of these medical therapies, on the other hand, are exceedingly low. While the advantages always outweigh the risks, different ionizing radiations such as alpha, beta, and gamma rays are used under ideal settings to treat various types of cancers.

Agents of Infection

Top 10 causes of cancer: Agents of Infection
Top 10 causes of cancer: Agents of Infection

Infectious agents such as viruses, bacteria, and parasites, among others, can cause cancer or increase the risk of cancer development. Some viruses can disrupt the signaling that controls cell growth and proliferation. Furthermore, certain infections weaken the immune system, making it vulnerable to other cancer-causing disorders. Some viruses, germs, and parasites can also induce chronic inflammation, which can lead to cancer.

The majority of viruses linked to an increased risk of cancer can be passed from person to person via blood and/or other body fluids. You may lower your chance of infection by being vaccinated, avoiding having sexual contact, and not sharing needles.

HIV (Human Immunodeficiency Syndrome)- HIV-AIDS is the virus that causes acquired immunodeficiency syndrome (AIDS). Although HIV infection may not cause cancer, it does impair the immune system and makes the body less capable of fighting off other cancer-causing infections. HIV infection raises the risk of various malignancies, including Kaposi sarcoma, lymphomas (including non-Hodgkin lymphoma and Hodgkin disease), and cervix, anus, lung, liver, and throat cancers.

The majority of viruses linked to an increased risk of cancer can be passed from person to person via blood and/or other body fluids. You may lower your chance of infection by being vaccinated, avoiding having sexual contact, and not sharing needles.


Top 10 causes of cancer: Immunosuppression
Top 10 causes of cancer: Immunosuppression

Many organ transplant recipients are given medicines to suppress their immune systems so that the organ is not rejected by the body. These “immunosuppressive” drugs impair the immune system’s capacity to identify and eliminate cancer cells, as well as resist cancer-causing infections. HIV infection weakens the immune system and raises the risk of acquiring certain cancers.

According to studies, transplant patients are at an increased risk of developing a range of cancers. Some of these tumors are caused by infectious microorganisms, although not all of them. Non-Hodgkin lymphoma (NHL) and lung, kidney, and liver cancers are the four most prevalent cancers in transplant patients, and they occur at a higher rate than in the general population. The Epstein-Barr virus (EBV) causes NHL, whereas chronic hepatitis B (HBV) and hepatitis C (HCV) virus infection cause liver cancer. Lung and kidney cancers are not known to be connected to infection.

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Gene Mutations

Top 10 causes of cancer: Gene Mutations
Top 10 causes of cancer: Gene Mutations

The last one among the top 10 causes of cancer is gene mutation. Discovering certain types of genes that have a function in cancer is a big step forward in cancer research. Over 90% of cancers are discovered to have some type of genetic alteration. Some of these alterations are genetic, while others are random, suggesting that they occur spontaneously or as a result of environmental exposure (usually over many years).

Cancer Gene Types

The three basic categories of genes that can impact cell formation and are changed (mutated) in various forms of cancer are as follows:

  • Tumor Suppressor Genes: These genes identify abnormal cell growth and reproduction, such as cancer cells, and prevent them from replicating until the deficit is corrected.
  • Oncogenes: These genes control the proper development of cells.
  • Mismatch-Repaired Genes: These genes identify faults in DNA replication to build a new cell. If the DNA does not “match” perfectly, these genes fix the mismatch and correct the mistake.

Substances that Cause Cancer

Changes in particular genes fundamentally alter the process of our cells, resulting in cancer. Some of these genetic alterations occur spontaneously as DNA is duplicated throughout the cell division process. Others, on the other hand, are caused by environmental DNA damage. These forms of exposure include substances such as those contained in cigarette smoke and radiation such as UV rays from the sun.

Some cancer-causing exposures, such as cigarette smoke and sunlight, are avoidable. Toxins that are present in the air we breathe, the water we drink, the food we eat, or the materials we use at work, on the other hand, are more difficult to avoid.

The most likely carcinogens to damage human health include Aflatoxins, Arsenic, Beryllium, Crystalline Silica, Formaldehyde, Nickel-Compounds, Thorium, and Wood Dust.

How to prevent problems of cancer?

prevent problems of cancer
prevent problems of cancer

We had a comprehensive look at the Top 10 causes of cancer, many malignancies, according to most specialists, may be avoided or the risk of developing tumors reduced greatly. Depending on one’s point of view, some of the methods are easy, while others are more severe. The most basic cancer prevention technique is to avoid its probable causes. Most clinicians and researchers prioritize quitting (or, better still, never starting) smoking. Many toxins and poisons, as well as excessive sunlight (by limiting exposure or wearing sunscreen), are useful cancer-prevention techniques. Some cancers can be averted by avoiding contact with specific viruses and illnesses. Chemists, X-ray technicians, ionizing radiation researchers, and asbestos workers should take all essential measures when working in close proximity to cancer-causing substances.

If, after reading the article “Top 10 causes of cancer “, you liked it and became interested in studying other fields of health and medicine, we suggest you read the following articles from the category cancer on our website.


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HealthoWealth Team

A group of students from prestigious universities are present in Healthowealth team. This group use reliable scientific sources and work under the supervision of experts and specialists to gather beneficial info in a simple way for public usage. This info is collected from authentic sources and with great precision, but keep in mind that if you have a serious illness, at first visit a specialist to be treated by doctors order. At least avoid self-medications!

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